In general, physicians hold the following view: pathogenesis is unclear, diagnosis is difficult, and treatment is symptomatic. Fibromyalgia is incurable. For the first time, the realization that in the case of fibromyalgia, the acupuncture points are recognized as acupuncture holes which glue up breaks new ground concerning the accuracy of diagnostics as well as the causal treatment. As a result of physical and/or mental stress, the free nerve endings are enclosed by protein, which clots on the spot and seals up the openings. The clotted openings can be cleaned surgically in such a way that they possibly do not glue up again. The stress occurring within the fibrous bundles can be relieved. Relief incisions make sense, in a word, the subtleties of hand surgery and peripheral neurosurgery including microsurgical techniques is necessary. The realization that there are real “switch boxes of meridians” on the arms and the legs allows to perform an operation in the course of which the 6 – 8 acupuncture points dominating one quadrant are examined requiring one single incision. The stress theory includes without the slightest difficulty, all the common factors which can worsen an existing fibromyalgia or cause a latent FMS to break out. Weather, draught, cold, a too rigorous training, house-construction, renovation, hormonal changes, strokes of fate, and mental stress. However, illnesses, virus and bacterial infections, injuries, real rheumatism, lupus, thyroid diseases should be considered as well. Many factors, but only one mechanism!